Irritable bowels are mean,
Plus they’ve no manners or hygiene;
They’re quick to insult or curse,
But what’s decidedly worse,
Is their disdain for being wiped clean.
See also this limerick’s Vocal Orifices companion pieces:
According to aboutibs.com, Irritable Bowel Syndrome (IBS) affects between 25 and 45 million people, or about 12 percent of the population, in the U.S. Two-thirds are women and girls, and most are 50 or younger. Estimates put sufferers of IBS worldwide at somewhere between nine and 23 percent of the population.